The gold standard for Rapid Screening For Invasive Fungal Infection (IFI).
The Fungitell® assay measures levels of (1→3)-ß-D-glucan in serum. The detection reagent is a biological cascade based upon modified Limulus Amebocyte Lysate (LAL), an extract of the blood cells of the North American Horseshoe Crab. The assay is based upon a modification of the LAL pathway. The Fungitell® reagent is modified to eliminate Factor C and, thus bypassing the activated factor B, to only react to (1→3)-ß-D-glucan, through the Factor G-mediated side of the pathway. This renders the reagent highly specific for (1→3)-ß-D-glucan and does not react to other polysaccharides, including beta-glucans with different glycosidic linkages.
Less than 60 pg/mL
≥ 80 pg/mL