Control Standard Endotoxin (CSE) is a widely used standard for endotoxin testing. It is a purified extract of E. coli O113:H10, the same strain used for the United States Pharmacopeia and the European Pharmacopeia reference standard endotoxin (RSE).
CSE is used as an economic alternative to the RSE. CSEs are standardized against the RSE as indicated on the Certificate of Analysis, so that results can be reported in Endotoxin Units (EU) and International Units (IU). CSE can be used for all LAL testing.
CSE is used to make standard curves and controls when performing the LAL assay. The concentrations used are dependent on the type of assay (e.g., chromogenic, gel-clot, or turbidimetric) and for photometric methods, the detection range required.
Products
| Reference | Product name | Packaging | Categories |
|---|---|---|---|
| E0005-1 | Escherichia coli 0113:H10 0.5 µg / vial | 1 vial | Control Standard Endotoxin |
| EC010-5 | Escherichia coli 0113:H10 10ng/vial | 5 vials | Control Standard Endotoxin |
| DCV | Depyrogenation Control Vials | 10 vials | Control Standard Endotoxin |
| E0125-1 | Escherichia coli 0113:H10 125µg/vial High potency standard | 1 vial | Control Standard Endotoxin |